The following classes of documents related to the Clinical Trial Subject are appropriate as a basis for change for a Clinical Trial entity:

• Serious breach/deviation of GCP - Subject Informed Consent as per T.III.1
  the automatically assigned file name "vtiii1-serious-breach-inf-cons-ct.pdf"
  
• Serious breach/deviation of GCP - Subject Information as per T.III.2
  the automatically assigned file name " vtiii2-serious-breach-subj-inf-ct.pdf"
  
• Serious breach/deviation of GCP - Recruitment Advertising as per T.III.3
  the automatically assigned file name "vtiii3-serious-breach-recr-adv-ct.pdf"
  
• Serious breach/deviation of GCP - CRF design as per T.III.4
  the automatically assigned file name "vtiii4-serious-breach-crf-ct.pdf"