The following classes of documents related to the Clinical Trial Facilities and Staff are appropriate as a basis for change for a Clinical Trial entity:

• Decision to introduce a new Investigational Site as per T.V.1
  the automatically assigned file name "vtv1-decision-new-investig-site-ct.pdf"
  
• Decision to change principal investigator agreement as per T.V.2
  the automatically assigned file name "vtv2-agreement-principal investigator-amend-ct.pdf"
  
• Monitoring Audit Report as per T.V.3
  the automatically assigned file name "vtv3-1-monitoring-audit-report-org.pdf"
  
• Monitoring Audit Report Response as per T.V.3
  the automatically assigned file name "vtv3-2-monitoring-audit-report-response.pdf"